More information: Yanli Wang et al, Reconstructing 3D chromosome structures from single-cell Hi-C data with SO(3)-equivariant graph neural networks, NAR Genomics and Bioinformatics (2025).

The chemical structure of RNA is analogous to that of DNA. It is comprised of a sugar–phosphate backbone and four distinct nucleotide bases: adenine (A), cytosine (C), guanine (G) and uracil (U).

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The yeast nuclear endonuclease Rnt1 has a well-characterized role in the maturation of many ncRNA precursors. However, the scope and consequence of its function in mRNA degradation pathways is much ...

Transcription is the process by which an RNA polymerase synthesizes ribonucleic acid (RNA) using deoxyribonucleic acid (DNA) as a template. The RNA binding protein hnRNPL is recruited to chromatin ...

Complex traits are influenced by genes and the environment, but especially the latter is difficult to pin down. This important study uses C. elegans to demonstrate that non-genetic differences in gene ...