Image based on an x-ray crystal structure of a G-quadruplex formed from the DNA sequence found in human genomes. Sixty years after scientists described the chemical code of life — an ...

The promise of genome editing to help understand human diseases and create new therapies is vast, but technological limitations have limited advancement of the field. While existing editing ...

Researchers at Northwestern University found that DNA strand separation may require more force than previously thought when ...

The promise of genome editing to help understand human diseases and create new therapies is vast, but technological ...

High-resolution cryo-electron microscopy has revealed the structural mechanism by which human RAD51 mediates strand exchange during homologous recombination, a key DNA repair pathway.

Researchers mapped the organization of human retinal cell chromatin, the fibers that package 3 billion nucleotide-long DNA molecules into compact structures that fit into chromosomes within each ...

The DNA of human cells consists of a sequence of about 3.1 billion building blocks. ... They constantly untangle knots in the DNA strand and create new chemical bonds when a strand of DNA breaks ...

The DNA of human cells consists of a sequence of about 3.1 billion building blocks. Cells go to great lengths to maintain the integrity of this vast store of information. They constantly untangle ...

Researchers have mapped 50,000 of DNA's mysterious "knots" in the human genome. The innovative study of DNA's hidden structures may open up new approaches for treatment and diagnosis of diseases ...