A dedicated neural network was created for COSY, HMBC, and HSQC spectra to guarantee optimum detection of real NMR peaks for 2D experiments. For training, 5000 synthetic spectra were used.

To address these limitations, 2D NMR experiments generate spectra defined by two chemical shift axes (instead of one, as in 1D spectra), with signals that correlate pairs of different nuclei. Three ...

At the Swedish NMR Centre, we present a new deep neural network based on the WaveNet architecture (WNN), which is designed to grasp specific patterns in the 2D NMR spectra. In the context of ...

To test the methods, a 2D HPLC chromatogram (of biro ink) and two NMR spectra, one correlation spectroscopy (COSY) and one heteronuclear single quantum coherence (HSQC) spectra, were 3D printed. The ...

Numerous NMR pulse sequences create varied results, which can considerably help with the interpretation or structural assignment. COSY-45 and COSY-90 are among the most simple 2D NMR experiments, ...

2D NMR spectroscopy can be applied to determine concentrations of metabolites, depending on the method used. Heteronuclear experiments such as HSQC are not used to determine concentration, at ...

To verify the field regulation algorithm, we demonstrate a well-known two-dimensional NMR spectroscopy experiment in which cross peaks are resolved in a 16.3 MW powered magnet that provides a 25 T ...

Two-dimensional (2D) 1H-13C methyl correlated NMR is increasingly being recognized as a powerful tool to characterize the higher order structure (HOS) of monoclonal antibody (mAb) therapeutics. 2D ...