A new study published in the journal Brain Research provides evidence that chronic use of a lipid-based cannabidiol (CBD) nanoemulsion may help reduce anxiety and panic-like behavior by targeting ...

† Department of Biological Sciences, St. Mary’s University, San Antonio, Texas 78228, United States ‡ Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas 77840, ...

While there are many grades of CAH severity, they all involve excess androgens (male sex hormones like testosterone). Up to 95% of CAH cases involve a 21-hydroxylase deficiency, a key enzyme for ...

Classical forms of congenital adrenal hyperplasia are caused by a severe deficiency of 21-hydroxylase, an enzyme involved in steroid biosynthesis, which triggers excessive androgen production ...

The most common form of congenital adrenal hyperplasia (CAH) is a condition in which the deficiency of the 21-hydroxylase enzyme results in absent or very low cortisol production. CAH differs from ...

It is characterized by a dysfunctional sterol 27-hydroxylase enzyme, which leads to the pathologic accumulation of toxic byproducts such as cholestanol and bile alcohols. Common signs of CTX include ...

All patients were treated and were medically stable after 29 (2 - 60) months of follow up. Autoantibodies to 21-hydroxylase enzyme were positive in 16 (90%). At diagnosis, and subsequent follow up, ...

Prolyl hydroxylase domain protein 2 (PHD2, also known as egg-laying defective nine 1 ... In gastric cancer and prostate cancer, PHD2 affects tumor development by inhibiting the HIF-mediated hypoxia ...

From the Departments of Medicine (F.R., L.Z., K.Z., G.W., B.P.K., M.D., J.L.R.-F., P.E.C., R.M.S., S.K.M., L.T., M.G.Z., D.T.O.), Pharmacology (D.T.O.), Psychiatry (J ...

If you were born with nonclassical congenital adrenal hyperplasia, your body doesn’t make enough of a certain enzyme called 21-hydroxylase, which affects the amount of hormones your body makes ...

So as to rule out an 11-beta-hydroxylase enzyme deficiency given the high blood pressure levels associated with hypokalaemia, the deoxycorticosterone (DOC) level came back high at 2599 pg/ml, i.e.

Objective: Herein, we compared ambulatory blood pressure (ABP) between young adults with congenital adrenal hyperplasia (CAH) due to 21-hydroxylase enzyme (21OHase) deficiency and a control group.