Without the acidic hydrogen atoms it is not clear what forces would hold the structure together, especially as the negatively charged phosphates near the axis will repel each other. (2 ...

Structure-based drug design is the design and optimization of a chemical structure with the goal ... A novel antiviral targeting the SARS-CoV-2 PLpro protease shows strong efficacy in a mouse ...

Due to the high expression of CLDN18.2, an isoform of CLDN18, genomic profiling has demonstrated CLDN18.2 as a potential target with prognostic impact; we aimed to characterize the molecular and ...

Type 2 diabetes (T2D) presents a global health concern ... In light of our observations, we concluded that the availability of glucose as a simple source of energy, along with the disturbance of the ...

Center for High Pressure Science and Technology Advanced Research, Beijing 100193, People’s Republic of China ...

Ethan, who is studying for a PhD in the School of Chemical, Materials and Biological Engineering (CMBE), has had his undergraduate dissertation published in the Journal of Materials Science and ...