Edited by Nenad Blau, University of Heidelberg, Heidelberg, Germany, and accepted by Editorial Board Member Stephen J. Benkovic April 24, 2019 (received for review February 20, 2019) ...

Plenty of software features on your phone promise to make you more productive, with iOS 18 boasting more than its share. But the iOS 18.4 update takes things a step further, adding a new ...

Hypoxia inducible factors (HIFs) and their regulatory hydroxylases the prolyl hydroxylase domain enzymes (PHDs) are the key mediators of the cellular response to hypoxia. HIFs are normally ...

An 18-year-old single student without a previous history of psychiatric illness or substance abuse was referred to a neuropsychiatry service for an assessment of psychiatric symptoms associated with a ...

For example, depressive symptoms have been linked with hypodopaminergic transmission in the reward system (17), and dopaminergic stimulant agents augment the efficacy of antidepressants (18). On the ...

The most common type of CAH is 21-hydroxylase deficiency 1; for the remainder of this review, CAH indicates CAH due to 21-hydroxylase deficiency. CAH is a disease of multiple hormonal imbalances.

Cafestol (20 μg/mL) had no effect on lithocholic acid 6β-hydroxylase mRNA, another enzyme involved in bile acid synthesis. LDL-receptor, HMG-CoA reductase, and HMG-CoA synthase mRNAs were ...

The Supporting Information is available free of charge on the ACS Publications website at DOI: 10.1021/jacs.6b01563.