17 Alpha-Hydroxylase Deficiency (17OHD) is a rare genetic disorder caused by mutations in the CYP17A1 gene, which plays a crucial role in steroid hormone production. This condition leads to a ...

Sexual precocity and a testicular mass can result from a Leydig cell tumor or from simple virilizing CAH with adrenal ... and P450c17 (17 α-hydroxylase/17, 20 lyase), but no detectable mRNA ...

The TouCAHn trial is an open-label, global, phase 2 study designed to evaluate the efficacy, safety, and pharmacokinetics of atumelnant when administered for 12 weeks in people with CAH caused by ...

and pharmacokinetics of atumelnant when administered for 12 weeks in people with CAH caused by 21-hydroxylase deficiency. The study enrolled 28 patients across 3 dose cohorts with classic CAH on a ...

Detailed price information for Crinetics Pharmaceuticals Inc (CRNX-Q) from The Globe and Mail including charting and trades.

due to 21-hydroxylase deficiency. The CAHtalyst studies were the largest-ever clinical trial program in classic CAH, including 285 pediatric and adult patients. The CAHtalyst Pediatric study included ...