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北京大学基础医学院用单细胞轨迹推断发现调控脂肪生成的G蛋白偶联 ...
在高脂饮食(HFD)诱导的肥胖小鼠模型中,通过基因过表达和基因敲低实验进一步证实,ADGRD1促进脂肪生成,从而改善代谢稳态,而GPR39抑制脂肪生成,导致代谢紊乱。此外,通过分析2,400个ChIP-seq数据和1,204个RNA-seq数据,作者 ...
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