Recent work in The EMBO Journal describes a new hybrid post-translational modification of proteins, composed of a poly-ubiquitin chain that is attached to a target protein via a mono-ADP-ribose (MAR) ...

Melbourne-based researchers at the Walter and Eliza Hall Institute (WEHI) at the Parkinson's Disease Research Centre have ...

Researchers have revealed for the first time how a key protein linked to Parkinson's mutates, leads to cell death in the ...

A new study has uncovered a molecular mechanism by which rice cells perceive viral infections and initiate antiviral response ...

Ubiquitin-specific proteases play a critical role in regulating cell death pathways in breast cancer, affecting tumor ...

DelveInsight's Molecular Glues Market Insights report includes a comprehensive understanding of current treatment practices, ...

BPGbio CTO Vivek Vishnudas will present on the company's novel E2-based targeted protein degradation program at the TPD and ...

Such interplay is seen with ADP-ribosylation and ubiquitylation. For example, DELTEX E3 ligases were reported to ubiquitylate a hydroxyl group on free NAD + and ADP-ribose in vitro, generating a ...

Fruit fly mutants that have severe sleep deficits perform better at olfactory learning and memory tasks, according to a study published in the open-access journal PLOS Biology by Sheng Huang and ...

Study reveals the structure of PINK1 protein, offering fresh hope for Parkinson's patients through potential targeted therapies that address root causes.