Background: Recent developments have made the thrombin generation (TG) test accessible to the clinical laboratory. Therefore, the clinical interpretation of TG parameters has become of increasing ...

Henan Key Laboratory of Nanomedicine for Targeting Diagnosis and Treatment, Zhengzhou 450001, China ...

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RNAi therapy focuses on an anticoagulant known as antithrombin. It encourages the development of thrombin, a coagulant that helps blood clot. RNAi therapy can treat hemophilia A and B since it ...

See Walker et al. Illustration from a crystal structure of the coagulation factor thrombin inhibited by two drug–peptide nucleic acid (PNA) molecules (pink and purple) bound together by base ...

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血小板在动脉血栓的形成中扮演着至关重要的角色，因此对其聚集功能的检测显得尤为重要。传统的透光聚集测定（LTA）手段虽被广泛认可为金标准，但其所需的大量血液样本和复杂的操作程序，使得这项技术在临床应用、大规模筛查以及对珍 rar基因工具鼠的检测中受到了制约。近日，上海交通大学医学院附属第九人民医院心内科的张俊峰主任、张家毓教授与上海科技大学的刘一凡教授等团队在《纳米生物技术期刊》上发表了一项名为《N ...

Using electrochemically responsive metal–organic frameworks (MOFs) as host matrices to afford gating properties for functional guests is rather attractive but remains unexplored. Herein, a series of ...

Future research is warranted to compare direct oral anticoagulant types (eg, factor Xa inhibitors vs direct thrombin inhibitors) and to establish whether lead-in parenteral anticoagulation is a ...