Seven-transmembrane receptors (7TMRs), also known as G protein-couple receptors, are the largest class of transmembrane receptors and a common target for therapeutics. Initially thought to signal ...

More specifically, Cannabis is a controlled substance under the CDSA. Possession, trafficking, import, export and production of all varieties of Cannabis regardless of the tetrahydrocannabinol ...

Department of Chemistry, University of Pittsburgh, 219 Parkman Avenue, Pittsburgh, Pennsylvania 15260, United States ...

Our drug discovery model has identified two novel STAT3 SH2 domain inhibitors 323–1 and 323–2 (delavatine A stereoisomers) in a series of experiments. In silico computational modeling, drug affinity ...

Department of Pediatrics, The Second Affiliated Hospital of Anhui Medical University, Hefei 230601, China ...

Background: The increasing demand for natural alternatives in diabetes treatment has driven research into plant-derived metabolites, particularly essential oils (EOs) with bioactive properties. This ...

8a-tetrahydro-2H-chromene衍生物的高效构建。其反应具有操作简单、底物范围广等优点，不仅拓宽了Sadphos（Xu-Phos）的应用范围，而且为不对称多米诺Heck ...

近日，云南民族大学民族医药学院周敏教授团队与复旦大学化学系张俊良教授团队合作，在不对称催化多米诺Heck/Tsuji-Trost反应 ...