Chemistry Process Research and Development, Amgen Inc., Thousand Oaks, California 19320, Medicinal Chemistry, Amgen SF, South San Francisco, California 94080, Process ...

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The new chiral nonracemic homoallylic exo-alcohols 6, 7, 10 with (1R)(+)-camphor (1) and endo-alcohols 8, 9, 11 with (1R)-(-)-fenchone (2) skeleton were synthesized in high yields by the ...

xix, 632 pages : 26 cm "This book provides a noteworthy compilation ofthe groundbreaking methods of stereoselective synthesis, belonging to the repertoire of every modem practitioner of synthetic ...

Carbohydrate synthesis is dominated by methods for the stereoselective formation of carbon–oxygen bonds and the selective reaction of multiple hydroxyl (OH) groups. Fucoidan is a sulfated glycan ...

作为天然产物和生物活性分子中的活性中间体及重要结构单元，环丙烷始终是化学家们重点研究的分子体系。目前最通用的化学合成方法当属金属卡宾对烯烃的加成反应。目前已有研究报道采用手性金属配合物和工程化金属酶催化非活化烯烃与类卡宾试剂的不对称环丙烷化反应。最近 ...