One common, but lesser-understood symptom of HD is irritability. Irritability can be deeply distressing for the person with ...

Welcome to Brainland, the bustling, 24/7 theme park in your head. There’s Memory Maze, Logic Log Flume, and of course, the ...

New research suggests that Huntington’s disease could cause the brain to rewire, like a road detour. While connections between some brain cells are shut down, the traffic seems to get re-routed, ...

We’ve been following the development of uniQure’s HTT-lowering drug, AMT-130, from its genesis in the lab, to animal studies just a few years ago, and now through to their ongoing Phase 1/2 clinical ...

Seeking dental care and adhering to recommended routines is tough for lots of folks, even under the best of circumstances. Throw Huntington’s disease (HD) into the mix, and oral health can get even ...

Scientists are working to understand some of the earliest changes to DNA repair caused by Huntington’s disease (HD) – insights that could help uncover new therapeutics and new ways to target somatic ...

The one-year report from the TRACK-HD study demonstrates a number of changes in pre-symptomatic HD-mutation carriers ...

We’re pleased to announce the 2025 HDBuzz Prize! This year, the HDBuzz Prize is brought to you by the Hereditary Disease Foundation (HDF), who are sponsoring this year’s competition. Training the next ...

Animal models of Huntington's disease: what they tell us about the disease and how can they help develop new therapie ...