Objectives To describe the proportion of transvaginal ultrasounds performed in a University Hospital of Buenos Aires (Argentina), requested upon a health check. Method Cross-sectional study of a ...

Aims/background Lab test results likely drive two-thirds to three-fourths of medical decisions. Unfortunately lab test reports rarely mention, or put into context, the analytic and biologic variation ...

Objectives Alteplase is commonly recommended for acute ischaemic stroke within 4.5 hours after stroke onset. The Third European Cooperative Acute Stroke Study (ECASS III) is the only trial reporting ...

Evidence-based medicine (EBM’s) traditional methods, especially randomised controlled trials (RCTs) and meta-analyses, along with risk-of-bias tools and checklists, have contributed significantly to ...

Correspondence to Dr Elaine Lehane, Catherine McAuley School of Nursing and Midwifery, University College Cork, Cork T12 K8AF, Ireland; e.lehane{at}ucc.ie To highlight and advance clinical ...

Background Major depressive disorder is estimated by the WHO to affect more than 300 million people globally, making depression the leading cause of disability worldwide. Antidepressants are commonly ...

This paper forms part of a series of methodological guidance from the Cochrane Rapid Reviews Methods Group and addresses rapid qualitative evidence syntheses (QESs), which use modified systematic, ...

BMJ Evidence-Based Medicine (BMJ EBM) publishes original evidence-based research, insights and opinions on what matters for health care. We focus on the tools, methods, and concepts that are basic and ...

Correspondence to Professor Kari A O Tikkinen, Department of Urology, Helsinki University Hospital, Helsinki 00290, Finland; kari.tikkinen{at}helsinki.fi To practice high quality healthcare, ...

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This paper is part of a series of methodological guidance from the Cochrane Rapid Reviews Methods Group. Rapid reviews (RRs) use modified systematic review methods to accelerate the review process ...

Non-randomised studies assessing COVID-19 vaccine effectiveness need to consider multiple factors that may generate spurious estimates due to bias or genuinely modify effectiveness. These include ...