Let’s explore the evidence-based benefits, possible side effects, and best practices for using milk thistle for liver health.

The flavonoid silymarin and one of its structural components, silibinin, are substances with documented hepatoprotective properties. Their mechanisms of action are still poorly understood.

It has been shown in rats that silibinin protects neonatal hepatocytes from cell damage produced by erythromycin, amitriptyline, nortriptyline and TBH. [21] The cytoprotective activity of ...

I’m from a thistle and can help your liver. What molecule am I? Silymarin has been used in traditional medicine for centuries; it is even alluded to in the Old Testament (Genesis 3:18). Ancient ...

Background: The incidence of intestinal fibrosis in Inflammatory bowel disease has increased in recent years, and the repair process is complex, leading to substantial economic and social burdens.

Our drug discovery model has identified two novel STAT3 SH2 domain inhibitors 323–1 and 323–2 (delavatine A stereoisomers) in a series of experiments. In silico computational modeling, drug affinity ...

Publications for 2024 can be found here. A case of fatal paralytic shellfish poisoning in Alaska. Temple C, Hughes A.Clin Toxicol (Phila). 2022 Mar;60(3):414-415. doi: 10.1080/15563650.2021.1967373.

Cancer is a disease that has achieved significant morbidity and mortality rates worldwide. It is characterized by the rapid and disorganized hyperproliferation of cells. Cutaneous melanoma, a type of ...