China has issued a notification of patent grant to bioAffinity for its novel method of using siRNAs to selectively kill ...

Detailed price information for Generation Bio Co. (GBIO-Q) from The Globe and Mail including charting and trades.

siRNA-based therapy is a new approach for the treatment of diseases, including cancer, viral infections, and so forth. When liposomes serve as an effective siRNA carrier, unveiling the siRNA-liposome ...

This groundbreaking work entitled "Novel injectable polypeptide nanoparticle encapsulated siRNA targeting TGF-β1 and COX-2 for localized fat reduction I: Preclinical in vitro and animal models", ...

HONG KONG, GERMANTOWN, Md., and SUZHOU, China, Sept. 19, 2024 /PRNewswire/ — Sirnaomics Ltd. (the “Company“, Stock Code: 2257, together with its subsidiaries ...

This approach leverages the natural uptake mechanisms of cells for fatty acids, thereby “tricking” cells into absorbing the siRNA for targeted gene repression. The lead candidate, DTx-1252, targets ...

Recent developments, such as the approval of new siRNA-based drugs and advancements in delivery mechanisms are signaling a promising era for gene-targeted therapies. The siRNA technology sector is ...

Mechanism of siRNA action. The method by which siRNA causes the silencing of genes is as follows: Double-stranded RNA is cleaved by the Dicer enzyme. This forms siRNA.

siRNA interference, commonly referred to as gene silence, is a biological mechanism that inhibits gene expression in disorders such as cancer. It may enhance the precision, efficacy, and stability of ...

Traditional peptide-mediated siRNA transfection via peptide transduction domains exhibits limited cytoplasmic delivery of siRNA due to endosomal entrapment. This work overcomes these limitations with ...