Rheumatoid arthritis (RA) is often called seropositive or seronegative. Seropositive refers to the presence of RA autoantibodies in the blood. Seronegative means these autoantibodies are not in the ...

The inclusion criteria were being age ≥ 18 years, having nonerosive peripheral arthritis lasting longer than six months, and having dual seropositive (rheumatoid factor (RF) and anti-citrullinated ...

High antibody titers of anti–citrullinated peptide antibodies, rheumatoid factor, and certain baseline factors predict RA ...

The following is a summary of “Dual seropositive nonerosive lupus arthritis: rhupus or not?” published in the February 2025 issue of Advances in Rheumatology by Pekdiker & Kara. Researchers conducted ...

Recombinant IL-40 up-regulated IL-1β, IL-6 and IL-8 (p<0.05 for all) in vitro. Conclusion We showed that IL-40 is significantly up-regulated in seropositive ERA and decreases after conventional ...

During a live event, Catherine J. Lee, MD, MS, discussed the efficacy and safety results of various trials of approved agents ...

The presence of anti-CD4 autoantibodies in treatment-naive patients with advanced HIV was associated with a decreased rate of CD4 reconstitution following ART initiation.

It is important for improvement of RA therapy to understand when and what changes occur in patients developing RA. This is true for both seropositive and seronegative patients. Activation of the ...

German researchers say the answer may be in virus-reactive memory T cells, which are triggered by COVID infection.

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A significant percentage of patients with RA and ANCA positivity were also diagnosed with AAV, with GPA being the most common subtype.