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We report the development, as well as the in vitro and in vivo testing, of a sprayable nanotherapeutic that uses surface engineered custom-designed multiarmed peptide grafted nanogold for on-the-spot ...
髓鞘在中枢神经系统中的功能. 髓鞘作为包裹轴突的多层膜结构,是脊椎动物神经系统的独特进化适应。它不仅通过节点跳跃传导(saltatory conduction)加速神经冲动传递,还通过少突胶质细胞(OLs)代谢支持轴突完整性。
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Autophagy is a major catabolic degradation and recycling process that maintains homeostasis in cells and is especially important in postmitotic neurons. We implemented a high-content phenotypic assay ...
Pathological representation of saltatory conduction in a myelinated axon in normal and pathological states. (A) Accumulating positive charge causes sodium channels to open at a threshold, allowing an ...
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