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A 9-year-old girl from Delhi with neurofibromatosis type 2 and congenital pseudoarthrosis successfully undergoes surgery to ...
In the study, treatment with AGA111, a recombinant human bone morphogenetic protein 6 (rhBMP6), led to faster radiographic fusion and a higher fusion success rate, as well as greater improvements in ...
Although lumbar spinal fusion is a commonly performed spinal procedure, it can result in significant morbidity, including nonunion or pseudarthrosis. Patients with nonunion following spinal fusion ...
As well as its allogeneic programme with NVDX3, Novodip’s lead autologous therapy, NVD003, is set to enter a Phase III trial as a potential treatment for congenital pseudarthrosis of the tibia ...
While the soft mechanics and tunable cell interactions facilitated by hydrogels have attracted significant interest in the development of functional hydrogel-based tissue engineering scaffolds, ...
另一方面,传统的评估方法,如普通 X 线检查,难以清晰显示骨融合的细节,对于判断融合程度和是否存在假关节形成(pseudarthrosis)存在较大局限性。此外,由于青少年正处于生长发育阶段,常规 CT 检查的高辐射剂量可能会对他们的身体造成潜在危害 ...
但在实际临床应用中,ACCF 术后假关节形成(pseudarthrosis)这一并发症却给患者的康复带来了巨大挑战。假关节形成意味着椎体间未能实现预期的骨性融合,这不仅会破坏脊柱的稳定性,引发颈部疼痛,还可能导致手术失败,增加再次手术的风险。更为棘手的是 ...