PGs and thromboxane A 2 (TXA 2), collectively termed prostanoids, are formed when arachidonic acid (AA), a 20-carbon unsaturated fatty acid, is released from the plasma membrane by phospholipases and ...

Prostanoids, consisting of the prostaglandins (PGs) and thromboxanes (Txs), are arachidonic acid (AA) metabolites synthesized in response to various physiological and pathophysiological stimuli (see ...

ABSTRACT: Sepsis-related haemostatic disorders, especially disseminated intravascular coagulation (DIC), substantially impact morbidity and mortality; nevertheless, early diagnosis is difficult due to ...

Table 1. Suggested strategies for analgesic/anti-inflammatory treatment and cardiovascular prevention among patients with inflammatory disease and different levels of risk of vascular events ...

Meloxicam is an enolcarboxamide with preferential COX-2 inhibitory activity. In vitro studies with human tissues have confirmed the high affinity of meloxicam for COX-2, whereas COX-1 was ...