Perturb-FISH推进了细胞内回路的功能基因组学研究,并为细胞间回路的遗传学研究提供了丰富的分子细节。 该方法不仅能够揭示细胞内扰动的分子机制,还能解析细胞间相互作用的复杂网络,为理解细胞在组织尺度上的功能提供了新的视角。
The researchers next showed that when macrophages were exposed to inflammatory signals, their activity changed alongside ...
最近,科学家们通过抑制特定基因并测量其对其他基因表达的影响,能够在单个细胞中探索基因回路。然而,这些方法未能捕捉到空间信息,例如细胞之间的相互影响,而这些信息对于理解细胞或基因在健康和疾病中的作用至关重要。
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The commonly used perturb and observe (P&O) and incremental conductance (INC) methods have advantages such as ease of implementation, but they also have the challenge of selecting the most optimized ...
▎药明康德内容团队编辑编者按:去年4月,一家名为Xaira Therapeutics的人工智能新锐公司正式走入产业视野。该公司由ARCH Venture Partners与Foresite ...