1 Surgical Research Unit 900, Department of Surgery L, Aarhus University Hospital, Aarhus Amtssygehus, Aarhus, Denmark 2 Department of Clinical Biochemistry, Aarhus University Hospital, Skejby Sygehus ...

In this article, the epidemiology of hepatocellular carcinoma (HCC), risk factors for the development of HCC, and how these factors affect the decision about whether an individual should or should ...

Background Multigene panel testing by next-generation sequencing (MGP-NGS) enables the detection of germline pathogenic or likely pathogenic variants (PVs/LPVs) in genes beyond those associated with a ...

Enhancing variant interpretation in hereditary cancer testing with RNA analysis from residual blood samples. Paired DNA/RNA genetic testing to uncover cryptic pathogenic variants (PV) associated with ...

Inherited mutations in the mismatch repair (MMR) genes MSH2 and MLH1 are found in most hereditary nonpolyposis colon cancer (HNPCC) patients studied 1.Eukaryotic MMR uses two partially redundant ...

Irritable bowel syndrome (IBS) and colon cancer symptoms can look alike. However, unlike IBS, colon cancer may cause bloody stool, fatigue, and unexplained weight loss, among other unique symptoms ...

One of the strongest predictors of colorectal cancer risk is carrying a germline mutation in a DNA mismatch repair (MMR) gene. Once identified, mutation carriers can be recommended for intensive ...

Multitarget stool DNA tests — which are becoming more popular in the United States — have shown increased sensitivity over fecal immunochemical tests (FITs) for early colorectal cancer (CRC ...

Absence of Progression As Assessed by Response Evaluation Criteria in Solid Tumors Predicts Survival in Advanced GI Stromal Tumors Treated With Imatinib Mesylate: The Intergroup EORTC-ISG-AGITG Phase ...