Late Breaker Oral Presentation to Include New Data from Cohort 1 of the MyPEAK™-1 Phase 1b/2 Clinical Trial of TN-201SOUTH ...
Phase 1b/2 Clinical Trial of TN-201 for Treatment of MYBPC3-Associated Hypertrophic Cardiomyopathy MyPEAK-1 Cohort 1 Data ...
and increasing TN-201 mRNA and MyBP-C protein levels over time. Circulating biomarkers of cardiac muscle strain and injury remained largely stable, and certain clinical markers of disease remained ...
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研究人员在研究过程中运用了多种关键技术方法。冷冻电镜(cryo-EM)和冷冻电子断层扫描(cryo-ET)技术被用于观察粗细肌丝的精细结构以及相关蛋白,如 titin 和 MyBP-C;X 射线衍射技术则用于分析肌丝的结构和状态;此外,还通过生化实验研究 Myosin 的各种特性 ...
and increasing TN-201 mRNA and MyBP-C protein levels over time. Circulating biomarkers of cardiac muscle strain and injury remained largely stable, and certain clinical markers of disease remained ...
and increasing TN-201 mRNA and MyBP-C protein levels over time. Circulating biomarkers of cardiac muscle strain and injury remained largely stable, and certain clinical markers of disease remained ...