Polo-like kinase 1 (PLK1) is a conserved regulator of cell division. During mitotic prophase, PLK1 contributes to the activation of the cyclin-dependent kinase 1 (CDK1). However, the exact functions ...

研究人员构建基于术前 CT 特征的列线图预测胃肠道间质瘤（GIST）mitotic 指数，可有效术前风险分层，指导临床决策。 胃肠道间质瘤（Gastrointestinal stromal tumors，GIST）是一种起源于间质 Cajal 细胞的潜在恶性肉瘤，也是胃肠道最常见的间叶肿瘤。全球每百万人中就 ...

This important study provides solid evidence that glucosylceramide synthase (GlcT), a rate-limiting enzyme for glycosphingolipid (GSL) production, plays a role in the differentiation of intestinal ...

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Using an unbiased approach, this important study discovered a role of Ezh2 in the differentiation of granule neuron precursors, the cell of origin for Shh group of medulloblastoma. Furthermore, the ...

RECKGIST score may predict recurrence in neurofibromatosis type 1 GISTs, potentially guiding treatment decisions, according ...

Discover how artificial intelligence and machine learning are transforming dermatopathology by improving diagnostic accuracy, ...

The real-time assessment is made possible by integrating Aiosyn’s pathology platform into Pramana’s AI edge compute ...

Cancer researchers at Children's Medical Research Institute have discovered an "unexpected mechanism" that our cells use to ...