This proliferation relies on the initiator caspase Dronc, and occurs independent of JNK, ROS or mitogens associated with the previously characterized Apoptosis-induced Proliferation (AiP) mechanism.

Conversely, human females have higher levels of IgM and respond more effectively to vaccinations. Furthermore, females tend to exhibit stronger responses in areas such as allograft rejection, in vitro ...

During fibrosis, (myo)fibroblasts deposit large amounts of extracellular matrix proteins, thereby replacing healthy functional tissue. In liver fibrosis, this leads to the loss of hepatocyte function, ...

We are entering an era of medicine where increasingly sophisticated data will be obtained from patients to determine proper diagnosis, predict outcomes and direct therapies. We predict that the most ...

Neuropathic pain (NPP) is caused by damage to the somatosensory nervous system. Its prominent symptoms are spontaneous pain, hyperalgesia and abnormal pain. This pain is long-lasting and unbearable, ...

Professor Peter Weissberg, Box 110, Division of Cardiovascular Medicine, Addenbrooke's Centre for Clinical Investigation, Addenbrooke's NHS Trust, Hills Road ...

The study conducted by Fang et al. offers significant and fundamental insights, notably enhancing our understanding of angiogenesis. While some of the claims are supported by convincing experimental ...