Find more information on the Altmetric Attention Score and how the score is calculated. The microsomal epoxide hydrolase (mEH) plays a significant role in the metabolism of xenobiotics such as ...

SOLUBLE blood group A and H substances from hog gastric mucosa consist of a protein ‘backbone’ to which numerous oligosaccharide units are attached 1,2.These oligosaccharide units are supposed ...

Disruptions in B-lp production perturb yolk morphology, readily allowing for visual identification of mutants with altered B-lp metabolism. Here we report the discovery of a missense mutation in ...

Microsomal triglyceride transfer protein (MTP) inhibitors might provide an alternative way to lower LDL-cholesterol levels. We tested the safety and LDL-cholesterol-lowering efficacy of an MTP ...

Wilson, M. H.; Rajan, S.; Danoff, A.; White, R. J.; Hensley, M. R.; Quinlivan, V. H.; Thierer, J. H.; Busch-Nentwich, E. M.; Hussain, M. M.; Farber, S. A. Microsomal ...

Oncogenic RAS mutations are among the most common in human cancers. To target the active, GTP-bound state of RAS(ON) directly, we employed an innovative tri-complex inhibitor (TCI) modality. Formation ...

The liver stands as one of the body’s most resilient organs, capable of remarkable regeneration even after sustaining significant damage from years of alcohol consumption. This vital organ ...

1 State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China 2 Haihe Laboratory of Modern Chinese Medicine, Tianjin University of ...