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The shortening of ABCG2 mRNA 3’UTR in the exosome-donor and -recipient cancer cells was investigated by 3’RACE assay. MicroRNA microarray was conducted to identify differentially expressed microRNAs ...
“在我们的研究中,我们专注于一种叫做miRNA-27a的分子,我们发现它通过抑制NF-κB通路发挥抗炎作用,但也可能通过激活Wnt和BMP信号来促进组织再生。通过在hDPSC中过度表达miRNA-24a,我们探索了它如何引导这些细胞成为硬组织形成细胞。” 最初,科学家利用基于 ...
Abstract: Microarray data-based cancer detection advances early diagnosis and personalized medicine by utilizing gene expression data to develop comprehensive cancer profiles, measuring thousands of ...
尽管诊断技术取得了显著进展,但肺癌仍然具有高度致命性,这主要是由于晚期诊断和侵袭性转移。最近的研究强调了微小RNA(miRNA)在肺癌发病机制中的关键作用。这些小的非编码RNA分子通过与信使RNA(mRNA)结合来调节基因表达,从而导致翻译抑制或降解。
which enables the capture of 180,000 human coding exons as well as nearly 550 microRNA exons. As Roche NimbleGen and others advance the use of microarrays for sequence capture, a company called ...
Hair growth is affected by circulating exosomes in the plasma, and sheep wool fiber thickness is altered by intravenous injection of miRNA mimics. Methods: This study investigated the effect of miRNAs ...
This useful study explores the role of RAP2A in asymmetric cell division (ACD) regulation in glioblastoma stem cells (GSCs), drawing parallels to Drosophila ACD mechanisms and proposing that an ...
Explore the NBA Draft 2024 with our free NBA Mock Draft Simulator & be the GM of your favorite NBA team. Mirna Habib's story was posted on the eve of the playoff tie between the Houston Rockets ...
Here, we have established the role of a highly conserved microRNA, miR-19b, in controlling proliferation in the embryonic avian forebrain, by regulating the expression of E2f8, a cell-cycle inhibitor ...
Study of the genetics of rheumatoid arthritis (RA) began about four decades ago with the discovery of HLA-DRB1. Since the beginning of this century, a number of non-HLA risk loci have been identified ...