Bayer seeks Japanese marketing authorization for low-dose contrast agent, gadoquatrane for contrast-enhanced MRI of all body regions and CNS: Berlin Tuesday, June 3, 2025, 13:00 H ...

PAS-004 demonstrates preliminary clinical activity as a monotherapy in patients with heavily pre-treated, refractory solid ...

Phase 1 study of zavondemstat (TACH101), a first-in-class KDM4 inhibitor, in patients with advanced solid tumors: Results on safety, pharmacokinetics, and anti-tumor activity. Pertuzumab plus ...

Vancomycin 265/309 (85.8%) 76/265 (25.3%) 198/309 (64.1%) † Clinical cure is resolution of diarrhea following the recommended dose of drug (fidaxomicin: 200 mg twice a day; vancomycin: 125 mg ...

Get article recommendations from ACS based on references in your Mendeley library. Pair your accounts.

School of Biology and Engineering (School of Health Medicine Modern Industry), Guizhou Key Laboratory of Macrocyclic and Supramolecular Chemistry, Guizhou Medical University, Guiyang 561113, P. R.

PeptiDream’s macrocyclic peptides can either act as medicines in their own right or can serve as targeting mechanisms for another therapeutic payload. In this case, the partners will work on ...

The World Health Organization (WHO) today posted an outbreak notice about a rise in COVID activity in three of its regions, ...

The Swiss drugmaker says the safety and efficacy of zosurabalpin will be investigated in a study involving 400 patients with ...

A screen of macrocyclic peptides identified a peptide that binds to SHOC2 and disrupts SHOC2–NRAS(Q61R) interactions at sub-micromolar concentrations. Insight from the X-ray co-crystal structure ...

A recent study presents macrocyclic tau-mimicking peptides that structurally and functionally resemble these disease-associated folds, providing new tools for studying tau aggregation and ...