Using quantitative proteomics, the authors uncover that ZMAT3 knockout leads to upregulation of HKDC1, a gene linked to mitochondrial respiration, and that ZMAT3 suppresses HKDC1 expression by ...

Gene editing could be used to treat millions of glaucoma patients. Glaucoma is a leading cause of blindness, characterized by ...

Myocarditis, or inflammation of the heart muscle, is of particular concern among mRNA vaccine opponents. An analysis published in 2022 found that myocarditis occurred in about 31.2 cases per 1 ...

Methods for tracking RNA inside living cells without perturbing their natural interactions and functions are critical within biology and, in particular, to facilitate studies of therapeutic RNA ...

The qPCR assays can be operated in parallel within a 5184-well nanoliter qPCR (nL-qPCR) chip at a single annealing temperature and buffer condition. We developed a robust bioinformatics approach to ...

A new type of mRNA vaccine is more scalable and adaptable to continuously evolving viruses such as SARS-CoV-2 and H5N1, according to a study by researchers at University of Pittsburgh School of ...

Trans amplifying mRNA vaccine expressing consensus spike elicits broad neutralization of SARS CoV 2 variants. npj Vaccines , 2025; 10 (1) DOI: 10.1038/s41541-025-01166-1 Cite This Page : ...

A new type of mRNA vaccine is more scalable and adaptable to continuously evolving viruses such as SARS-CoV-2 and H5N1, according to a study by researchers at the University of Pittsburgh School ...

Created primarily to process qPCR Cq data for graphical output. However, the functions included is generic and good for other use. This package includes functions to calculate the fold change using ...

Republican lawmakers and federal health officials alike are shunning messenger RNA, a basic building block of biology that proved its value during COVID, and that holds promise for combating the ...