The frequency at which we observed heptamer seed matches in the 5′ UTR, ORF and 3′ UTR of experimental ... between an siRNA and any given mRNA is not associated with off-target identity.

With a browser that shows the region of an mRNA that is expressed, they made the surprising observation that a number of genes in dopamine neurons showed abundant expression of 3'UTR mRNA ...

When they sequenced the mRNA, they noticed that for many transcripts there were thousands of copies of the 3'UTR, but virtually none of the coding region. To see if this was a common occurrence, the ...

The Lai lab uses an integrated approach to study selected topics in mRNA processing and modification ... was the realization that hundreds of genes utilized unannotated 3’ UTR extensions in the ...

When they viewed the expression patterns for the isolated mRNA, to their surprise they observed that some genes in dopamine neurons showed abundant expression of 3′ UTR mRNA sequences and little ...

have analyzed global changes in mRNA length in a murine model of atherosclerosis progression. They observed variations in the ...

Chief Medical Officer (Adult Cancers), UTRx Inc. “The validation data supports the technological abilities of engineering mRNA stability elements on the 3’UTR of oncogenes for therapeutic use ...

After transcription, each mRNA molecule possesses in its middle a coding sequence, the instructions from which the protein will be made. The coding sequence is flanked by two sections that do not go ...