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EyeBio’s main asset is Restoret, an intravitreally delivered trispecific antibody that acts as an agonist of the Wnt signalling pathway and is in the phase 1b/2a AMARONE study in DME and ...
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“There are two advanced forms of AMD: the wet form or neovascular form, [for which] there are treatments, there are medicines we inject intravitreally in patients routinely, and we’ve been ...
The recombinant human vascular endothelial growth factor receptor (VEGFR)-antibody human complement receptor 1 (CR1) fusion protein will be intravitreally administered in up to 150 patients.
Investors now have three ASX-listed stem cell therapy companies to choose from – and we can thank Mesoblast for inspiring the third.
We use gold nanorods and patterned near-infrared laser. We intravitreally injected the gold nanorods into the eye and then when they attach to the retina, we project with a patterned near-infrared ...
The use of viral vectors to deliver genes to the nervous system shows great promise for both basic research and therapeutic applications. However, the brain presents a challenging target for gene ...
METHODS 15 patients with recent onset CRVO (from 1–21 days' duration, mean 8 days) were given 75–100 μg of tPA intravitreally associate with low dose low molecular weight heparin. CRVO was perfused in ...
*Syndromes include WNF, West Nile meningitis, West Nile encephalitis and WNP. ‡ Overall, WNND represents 1% of human WNV infections. § WNP may occur in the context of any other manifestation of ...
This manuscript demonstrates that Oct4 overexpression synergizes with Notch inhibition (Rbpj knockout) to promote the conversion of adult murine Müller glia (MG) into bipolar cells. These findings are ...