Genentech Inc. has disclosed molecular glue compounds with the ability to induce cyclin-dependent kinase 2 (CDK2)/protein cereblon (CRBN) interaction for CDK2 degradation reported to be useful for the ...

Proxygen GmbH has divulged molecular glue degraders comprising a cullin-ring E3 ligase (CRL)-binding moiety acting as cyclin-dependent kinase 12 (CDK12)/cyclin K degradation inducers reported to be ...

The following is a summary of “Disruption of the sorcin‒PAX5 protein‒protein interaction induces ferroptosis by promoting the FBXL12-mediated ubiquitination of ALDH1A1 in pancreatic cancer,” published ...

The results identified plant resistance inducers (PRIs) among biopesticide products capable of protecting carrots against Alternaria leaf blight. By applying a PRI to a range of carrot varieties ...

This hole-in-the-wall restaurant in Shepherdstown is the perfect place to start your day with a delicious, home-cooked meal!

Marcia’s menu is a love letter to classic American breakfast fare, written in the language of butter and syrup. It’s the kind ...

In a live event, Ganesh V. Raj, MD, PhD, discussed the drug-drug interactions and outcomes by disease volumes across ARPI trials in mHSPC.

If taking both, watch for an increase in buspirone-related side effects. Certain antiepileptic drugs may interact with buspirone. These drugs are enzyme inducers, meaning they increase the metabolic ...

Is it Botox, fillers or a new facelift? While many celebrities are looking 20 years younger, everyone is wondering what they ...

The following is a summary of “Naldemedine Use and Healthcare Resource Utilization in Patients treated with Opioid Analgesics for Chronic Non-Cancer Pain: Results of a Real-world Study in the USA,” ...