A 3D engineered kidney glomerulus model replicates structural and mechanical features of the glomerular filtration barrier, ...

这项研究的核心策略之一，就是用单剂量的美法仑（melphalan）作为减毒预处理药物。与白消安的“全拆”不同，美法仑在较低剂量下可以更温和地清除部分造血干细胞，为基因改造细胞提供植入空间，同时又不至于完全摧毁患者自身的造血功能。这就像对城市进行“微创 ...

Table 1. Diabetic Nephropathy Stages: Cutoff Values of Urine Albumin for Diagnosis and Main Clinical Characteristics Stages Albuminuria cutoff values (ref. 14) Clinical characteristics (ref. no.) ...

有一种疾病，它让血液中的生命载体——红细胞，从充满活力的圆形变成了僵硬的镰刀状。这些异常的细胞在血管中横冲直撞 ...

In addition, the glomerular volume in those with hypertension was increased, suggestive of hyperfiltration. Those with hypertension had no evidence of obsolescent glomeruli, which would have ...

The present experiments were performed in β1/β2-adrenergic receptor–deficient mice (β1/β2ADR −/−) to assess the role of β-adrenergic receptors in basal and regulated renin expression and release. On a ...