OBJECTIVE To evaluate signs of haemolysis in babies of Rh-D negative mothers who underwent prophylaxis with anti-D immunoglobulin during pregnancy. DESIGN The following were evaluated in all babies of ...
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However, it is not an uncommon clinical practice to diagnose infants with HDN without evidence of haemolysis first being established with over-reliance on a positive DAT (box 2). In our clinical ...
While HS in this patient has been categorised as mild and is unlikely to require any intervention, the haemolysis is of clinical significance since it inadvertently delayed the diagnosis of diabetes.
In the setting of new anaemia and elevated bilirubin levels, there was suspicion of haemolysis. Therefore, reticulocytes, lactate dehydrogenase, haptoglobin, and fractionated bilirubin were ...
The clinical presentations were haemolytic-uraemic syndrome (26%), catastrophic APS (23%), acute renal failure (15%), malignant hypertension (13%), thrombotic thrombocytopenic purpura (13%), and HELLP ...
Preliminary results from the phase 1/2 BEACON trial of BEAM-101 showed evidence that the drug was able to normalise markers of haemolysis – the red blood cell destruction that is a feature of ...
The flavonoid silymarin and one of its structural components, silibinin, are substances with documented hepatoprotective properties. Their mechanisms of action are still poorly understood. However ...
which showed that crovalimab was as effective as Soliris at controlling the destruction of red blood cells (haemolysis) that characterises PNH, whilst also reducing the need for blood transfusions.
CONCLUSIONS Anaemia in SLE usually takes the form of ACD and IDA, however autoimmune haemolysis is not uncommon. SLE patients with different causes of anaemia differ in regard to several immunological ...
In SCD, chronic haemolysis and repeated episodes of hypoxia contribute to the development of PH. Symptoms include shortness of breath, chest pain, fatigue, and an increased risk of heart failure.
Two weeks after receiving his third cycle of treatment, he presented to the emergency department with altered mental status, acute kidney injury, fever, anaemia with labs suggestive of haemolysis and ...
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