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High-fructose corn syrup, prevalent in many processed foods, is a simple carbohydrate that offers minimal nutritional value and contributes to health issues like obesity. Derived from corn ...

High fructose corn syrup is found everywhere, especially in soft drinks, and it is so pervasive it has become a modern-day plague. Unfortunately, most Americans have no clue what we are up against ...

Background The prevalence of hyperuricemia and gout has increased in recent decades. The role of dietary fructose in the development of these conditions remains unclear. Objective To conduct a ...

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Hepatic effects of fructose. There is recent evidence that fructose can also act indirectly to boost hepatic gluconeogenesis. Fructose, but not glucose, can activate AMP kinase (AMPK) in certain ...

Heart failure is one of the leading causes of death worldwide and has been singled out as an emerging epidemic. 1, 2 With a 5‐year survival rate of 50%, heart failure poses a tremendous burden on our ...

†Current address: Merck Research Laboratories, 126 East Lincoln Avenue, Rahway, NJ 07065. ‡Current address: Jubilant Biosys, Bangalore, India. §Current address ...

Specifically, ALDOB, as a fructose-1,6-bisphosphate aldolase, also involves in the pentose phosphate pathway, carbon metabolism, and HIF-1 signaling pathway. CPS1, functioning as a carbamoyl-phosphate ...

Institut für Biochemie, Martin-Luther-Universität Halle-Wittenberg, Kurt-Mothes-Strasse 3, D-06099 Halle, Germany, Department of Biochemistry and Molecular Biology, The University of Queensland, ...

We used in silico methods to screen a library of 1,013 compounds for possible binding to the allosteric site in farnesyl diphosphate synthase (FPPS). Two of the 50 predicted hits had activity against ...