本研究针对帕金森病 (PD)患者肠道微生物代谢左旋多巴 (L-dopa)导致疗效降低的关键问题，开发了厚朴酚 (HNK)与短链脂肪酸 (SCFAs)的新型酯类衍生物。研究人员发现HNK-SCFA酯类能剂量依赖性地抑制粪肠球菌 (E. faecalis)生长，延缓L-dopa代谢为多巴胺，同时保留SCFAs的神经保护作用。该研究为通过调节肠道菌 ...

生物活性评估包括：DPPH法测抗氧化性；Kirby-Bauer法检测对E. faecalis（MTCC 2409）和P. aeruginosa（MTCC 2080）的抗菌活性；MTT法分析对HaCaT（人角质形成细胞）和MCF-7（乳腺癌细胞）的细胞毒性；鸡胚绒毛尿囊膜（CAM）实验评估血管生成调控；斑马鱼胚胎模型（6-72 hpf）观察发育毒性。

Periradicular lesions were induced by inoculating Enterococcus faecalis in the root canals. After confirming that a periradicular lesion developed, the root canals were treated within one or two ...

Os terpenos de alecrim (óleo essencial) por exemplo, além de possuírem um odor muito agradável, têm alta capacidade antioxidante, propriedades bactericidas contras as bactérias Streptococcus pyogenes, ...