We present a method for monitoring receptor dimerization at the membrane of live cells. Chimeric proteins containing the epidermal growth factor (EGF) receptor extracellular and transmembrane ...

Using truncation and missense mutants of Hsp90, we analysed the structural implications of its ATPase cycle. C‐terminal truncation mutants lacking inherent dimerization displayed reduced ATPase ...

One major function of the hypothalamus is to maintain homeostasis by modulating the secretion of pituitary hormones. The paraventricular (PVN) and supraoptic (SON) nuclei are major integration centers ...

Find more information on the Altmetric Attention Score and how the score is calculated. The dimerization of multimodular polyketide synthases is essential for their function. Motifs that supplement ...

G protein-coupled receptors (GPCRs) detect a wide variety of physical and chemical signals and transmit that information across the cellular plasma membrane. Dimerization is a proposed modulator of ...

Avenzo Therapeutics, Inc. ("Avenzo"), a clinical-stage biotechnology company developing next-generation oncology therapies, today announced initiation of a Phase 1/2 clinical study of its potential ...

Affibody molecules EGFR 125 I 111 In γ-camera imaging The epidermal growth factor receptor (EGFR; other designations are HER1 and ErbB-1) is a transmembrane tyrosine kinase receptor that regulates ...

A pair of recent studies from the laboratory of Bin Zhang, MD, Ph.D., the Johanna Dobe Professor of Cancer Immunology, have ...

在细胞中成千上万的RNA分子是如何准确无误地抵达各自的目的地，从而指导蛋白质的合成，调控复杂的生命活动？从疾病的发生发展到神经元的精细分化，RNA的“空间定位”（RNA ...

封面文章Synergistic Bulk and Surface Engineering via Rapid Quenching for High-Performance Li-Rich Layered Manganese Oxide ...

2025年05月07日 新闻网 浏览次数：5741 ...