Diastolic dysfunction is a heart condition that happens when there is a “stiffening” of the major pumping chambers of the organ (ventricles). This stiffness gets in the way of the heart’s ability to ...

BACKGROUND: Despite the high morbidity and mortality of heart failure with preserved ejection fraction (HFpEF), treatment ...

Discover how your sleep position can impact heart health and simple adjustments to promote better cardiovascular function.

A STUDY assessing coronary proximity in patients undergoing transcatheter pulmonary valve replacement (TPVR) with ...

A set of five criteria based on our own observations is presented with a review of the literature. The responsible mechanism for this seemingly paradoxical situation is not known. However, spontaneous ...

Ischaemia can occur due to the coronary steal phenomenon where blood is shunted away from coronary beds to the low-pressure pulmonary circulation during diastole, resulting in ischaemia in the ...

Correspondence to: Ramachandran S Vasan, MD, Framingham Heart Study, 73, Mt Wayte Avenue, Framingham, MA 01702, USA; vasan{at}fram.nhlbi.nih.gov ...

Background: A metabolic shift from fatty acid (FAO) to glucose oxidation (GO) occurs during cardiac hypertrophy (LVH) and heart failure with reduced ejection fraction (HFrEF), which is mediated by PGC ...