To test this hypothesis, we disrupted a murine homolog of a Drosophila nuage protein Maelstrom. Effects on male meiotic chromosome synapsis and derepression of transposable elements (TEs) were ...

In this case, translational derepression is induced through conserved signalling pathways by regulation both of general components of the translational machinery and of mRNA-specific repressors.

Department of Cellular and Molecular Pharmacology and Physiology (M.S., B.C.B.), University of Rochester School of Medicine and Dentistry, NY. Department of Medicine ...

Department of Gastroenterology, the Second Affiliated Hospital of Zhengzhou University, Zhengzhou, China Introduction: Inflammatory bowel disease (IBD) is a complex immune-mediated condition, and ...

Defective autophagy in macrophages leads to pathological processes that contribute to atherosclerosis, including impaired cholesterol metabolism and defective efferocytosis. Autophagy promotes the ...