Rec8 joins the whole length of the sister chromatids together, and, as meiosis proceeds, is lost in a stepwise manner that correlates with the loss of sister-chromatid cohesion. Figure 1 ...

这一过程伴随着染色体从间期的松散状态转变为有丝分裂期特有的杆状结构，其中涉及两个关键的结构变化：姐妹染色单体的分离（姐妹染色单体分辨率，sister chromatid resolution）和每条染色单体的折叠（染色体折叠，chromosome folding） 。这两个变化对于后续有丝 ...

↵‡ Ames test, sister chromatid exchange, chromosome aberrations, neutral red assay, lactate dehydrogenase release. ↵§ RJR has only reported inhalation studies using one rodent species for the products ...

2021), in which the repeat direction is parallel to the chromatid long axis. Our metaphase-cell data did not show evidence of edge-to-edge packing or 100- to 200-nm periodic structures. The simplest ...

Turmeric (Curcuma longa) (Figure 1), originating from India, is a curry spice that has garnered significant attention in recent decades due to its composition of bioactive curcuminoids—curcumin, ...

Background Gene amplification is a frequent manifestation of genomic instability that plays a role in tumour progression and development of drug resistance. It is manifested cytogenetically as ...