In general, the kinetochore position and the sister-chromatid cohesion site are spatially linked. Here, the authors find a meiosis-specific distal cohesion site decoupled from the kinetochore in ...

这一过程伴随着染色体从间期的松散状态转变为有丝分裂期特有的杆状结构，其中涉及两个关键的结构变化：姐妹染色单体的分离（姐妹染色单体分辨率，sister chromatid resolution）和每条染色单体的折叠（染色体折叠，chromosome folding） 。这两个变化对于后续有丝 ...

2021), in which the repeat direction is parallel to the chromatid long axis. Our metaphase-cell data did not show evidence of edge-to-edge packing or 100- to 200-nm periodic structures. The simplest ...