Polyphosphate (polyP) exists in all life forms; however, its biological functions in metazoans are understudied. Here, we explored Drosophila as the first genetic model to explore polyP biology in ...

To confirm that copper was the driving force behind these effects, the researchers used a copper-selective chelator — a compound that binds to copper and prevents it from interacting with cells.

Q4 2024 Earnings Call Transcript March 7, 2025 Operator: Good morning, and welcome to the Molecular Partners Fourth Quarter ...

Treating these mice with deferiprone, an FDA-approved iron chelator, delayed the onset of albuminuria even though anti-dsDNA IgG levels were similar to the vehicle treated group (136). Furthermore, ...

It involves some protein engineering, but it also certainly involves the linker chelator. And of course, we also do half-life extenders. Most importantly, however, for the patient's benefit ...

Journal of Nuclear Medicine February 2025, jnumed.124.268835; DOI: https://doi.org/10.2967/jnumed.124.268835 ...