2025年5月6日，专注于表观遗传重编程的初创企业 NewLimit 宣布完成 1.3 亿美元的 B 轮融资。本轮融资由凯鹏华盈（Kleiner Perkins）领投，Founders Fund、Khosla Ventures、Human ...

(C) CCAT1-L regulates MYC expression at the transcriptional level. A crude preparation of nuclei was subjected to nuclear run-on assay under the indicated conditions in HT29 cells.

Induced pluripotent stem cells have been generated from mouse and human adult fibroblasts without the tumor-causing gene c-Myc. Toward the end of the last century, the remarkable conjunction of ...

Viral-mediated Oct4 overexpression induces direct conversion of wildtype mammalian Müller glia to bipolar neurons, and this process is synergistically enhanced by loss of Notch signaling.

日本科学家山中伸弥发现，通过短暂激活四种关键转录因子（OCT4、SOX2、KLF4 和 c-MYC，统称 OSKM），可以使老化的人类皮肤细胞部分恢复年轻状态。

FLORENCE — The trial for one of two teens accused of capital murder in the shooting death of Miguel Antonio Adame was at a hearing Friday, during which the defendant did not issue a plea of ...

Scale bar, 100 μm. (B) Flow cytometry analysis of stem cell markers (OCT4, SOX2, SSAE4) of iPSC coated with Laminin 521 after several passages. (C) Immunofluorescence staining and flow cytometry ...

Advances in multi-omics, artificial intelligence (AI), deep learning (DL), ageing biomarkers, precision imaging, ageing clocks, robotics, and smart technologies have enabled researchers to ...

全球老龄化浪潮中，心血管疾病已成为人类健康的"头号杀手"。数据显示：65岁以上人群中心肌纤维化发生率超过60%，慢性心脏 ...