Here, the authors describe genetically engineering the Pseudomonas genome by two-step allelic exchange. Suicide vector-encoded alleles are used to generate mutations by homologous recombination at ...

A new study by the Genomics and Microbial Evolution Group at the Miguel Hernández University of Elche (UMH) together with the ...

Allelic dropout (ADO) is a common limitation of all PCR-based molecular diagnostic methods, leading to false-negative or false-positive results, depending on the allele that was dropped. We report a ...

Journal of Human Genetics - Identification and allelic frequencies of novel single-nucleotide polymorphisms in the DUSP1 and BTG1 genes Skip to main content Thank you for visiting nature.com.

Keywords: probiotics, immune modulation, gene expression, allelic variants, host genetics, polymorphism, immune response, personalized therapies Important note: All contributions to this Research ...

The promoter of the human imprinted gene MEST is differentially methylated with respect to the parent of origin and contains several non B-DNA motifs that are capable of forming G-quadruplexes. These ...

It reveals that its most dangerous form arises from a specific combination of genes and allelic variants that give it an advantage in the human intestine. This research could pave the way for new ...

Fifty years of outstanding neuroscience research studies have revealed many secrets of how drugs of abuse affect and change ...

Some of the most harmful genetic changes in cancer are also the hardest to see. These structural alterations, deep within a ...

There is significant variability in the efficacy and safety of oral P2Y12 inhibitors, which are used to prevent ischemic outcomes in common diseases such as coronary and peripheral arterial disease ...

Volume 642 Issue 8068, 19 June 2025https://www.nature.com/nature/volumes/642/issues/8068Editorial 社论In science’s new era, open and transparent cooperation remains key《科学新时代中，开放透明的合作仍是关键》Transparent pe ...

Recessive dystrophic epidermolysis bullosa (RDEB) is a systemic disease of poor mucocutaneous basement membrane integrity downstream of bi-allelic pathogenic variants in COL7A1. Cutaneous clinical ...