A comprehensive atlas maps DNA methylation across 39 human cell types, revealing a complex landscape of epigenetic regulation.

A new study has been published in Nature Communications, presenting the first comprehensive atlas of allele-specific DNA ...

Current techniques have their roots in allele-specific oligonucleotide hybridization (ASOH) 1. In its basic form (i.e., hybridization, stringent washing, and signal detection), ASOH is limited by ...

"The change in daily sleep patterns may be intertwined with cognitive aging, and may serve as an early marker or risk factor ...

Patients with Fuchs endothelial corneal dystrophy with particular genetic markers are at higher risk for surgery and vision loss.

Population-specific HLA allele and haplotype frequency distributions determine the probabilities to find matched donors in a stem cell donor registry of given size and ethnic composition. Results and ...

Researchers from Life Edit Therapeutics Inc. recently reported preclinical data on the application of their gene editing technology Life Edit CRISPR system to Huntington’s disease (HD).

Researchers have developed a comprehensive atlas that maps DNA methylation—a critical chemical modification governing gene ...

The Ancestral allele files provided were queried from the 1000 genomes AA field in the VCF files. These sites are all biallelic SNPs and only contains sites that were determined that it can be ...

Nonsteroidal anti-inflammatory drug use for over 2 years was associated with a lower risk for dementia, especially ...