Figure 1: Neuroprotection by bFGF is associated with increased expression of activin βA mRNA. Recently, a different type of interaction between bFGF and the TGF-β superfamily was reported from ...

1 Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, United States 2 Department of Urology, Beth Israel Deaconess Medical Center and Harvard Medical ...

Activin A 是一种多功能细胞因子，是TGF-β 超家族的成员。Activin A 首先与成员表面的 II 型激活素受体 (ActIIRA 或 ActRIIB) 结合，然后募集和磷酸化 I 型激活素受体 (ActRI)。Activin A 主要通过SMAD2/3 蛋白发出信号以调节多种功能，包括炎症、纤维化和肿瘤发生。 Activin以三 ...

The challenge of the obesity epidemic is widespread and one that even pediatricians face constantly,” a Connecticut doctor ...

Reuters, the news and media division of Thomson Reuters, is the world’s largest multimedia news provider, reaching billions ...

Keros Therapeutics' stock has plummeted over 70% due to safety issues in its phase 2 PAH study, halting all trial arms. Learn more about KROS stock here.

近日，国家卫生健康委员会主任宣布将持续推进“ 体重管理年”行动，鼓励医疗机构设立体重门诊，采用多学科干预手段帮助患者减重。这一举措无疑为减重市场注入了强大的动力，也预示着肥胖治疗领域即将迎来一场前所未有的变革。

为探究黑色素瘤中激活素 A（Activin-A）前体加工机制及对肿瘤生长影响，研究人员经 RNAi 筛选等研究，发现 Klk8 可调节其加工促肿瘤生长，为治疗提供新靶点。 在人体中，有一种名为激活素 A（Activin-A）的蛋白质，它属于转化生长因子 -β（TGF-β）家族，就像一个 ...

Arrowhead Pharmaceuticals, Inc. (NASDAQ: ARWR) today announced presentation of preclinical data supporting the advancement of two first-in-class clini ...

Hormones can be paracrine, endocrine or autocrine factors. The Activin-A precursor protein undergoes proteolytic processing by furin and other proteases. Here the authors identify that kallikrein ...

About a dozen drugmakers are developing new weight-loss treatments aimed at preserving muscle, and industry analysts, clinical trial experts and doctors say they may also need to demonstrate ...

周四，H.C. Wainwright重申对WAVE Life Sciences（NASDAQ:WVE）的买入评级，目标价为22.00美元，较当前10.57美元的价格有显著上涨空间。该公司分析师Andrew S. Fein分享了最近在加拿大班夫举行的Keystone肥胖和脂肪组织会议的见解。根据InvestingPro数据，WVE的分析师目标价区间为14美元至36美元，最近有三位分析师上调了盈利预期 ...