为探究巴豆酰辅酶 A（Crotonyl-CoA）在生物体内的代谢及功能，研究人员开展相关研究。发现 Crotonyl-CoA 存在于多种组织，ECHS1 和 CDYL 可将其转化，还能修饰蛋白质。这有助于深入理解细胞代谢与蛋白质功能调控机制。

Insufficient acetyl-CoA derails the immune system's ability to protect the body. Until now, however, it was unclear exactly how immune cells maintained their acetyl-CoA reserves.

A study from Van Andel Institute reveals that immune cells use two pathways, ACLY and ACSS2, to produce acetyl-CoA, an essential metabolite for fighting infection and cancer. These findings highlight ...

The initial step for such fatty acid synthesis is acetyl-CoA carboxylation to malonyl-CoA with the help of the enzyme acetyl-CoA carboxylase, which is mostly taking place in liver cells, but also ...