Cell polarity coordinates jellyfish larval development along a central axis, study finds
Scientists have uncovered a key mechanism in jellyfish embryos that provides new insights into how the body plan of these ...
Dewpoint Therapeutics Announces DPTX3496 as a Development Candidate for the Treatment of Colorectal, Breast, and Lung Cancers
Dewpoint Therapeutics’ second development candidate, DPTX3496 is an oral, small molecule acting via a novel ...
BioWorld6d
Dewpoint nominates second condensate modulator for Wnt-driven cancers
Dewpoint Therapeutics Inc. has nominated a second development candidate, DPTX-3496. The oral, small-molecule condensate modulator targets β-catenin to address Wnt-driven colorectal cancer, ...
eLife16d
Wnt specifically induces FZD5/8 endocytosis and degradation and the involvement of RSPO-ZNRF3/RNF43 and DVL
Frizzled (FZD) proteins are the principal receptors of the Wnt signaling pathway. However, whether Wnt ligands induce FZD endocytosis and degradation remains elusive. The transmembrane E3 ubiquitin ...
Hosted on MSN13d
Dietary choices significantly impact gene function and overall health
Short-chain fatty acids (SCFAs) like propionate and butyrate are critical byproducts of dietary fiber digestion. These ...
BioWorld16d
Wnt/PCP signaling mediators identified as new markers in yellow nail syndrome
Researchers from Tel Aviv Sourasky Medical Center presented data from a study that aimed to investigate the genetic mechanisms underlying yellow nail syndrome (YNS), a rare disorder characterized by ...
EurekAlert!1d
Cell polarity coordinates jellyfish larval development along a central axis
Scientists have uncovered a key mechanism in jellyfish embryos that provides new insights into how the body plan of these ...