Trispecific antibodies have become one of the most exciting frontiers in modern biotherapeutics, with more than 50 candidates currently in development. These innovative molecules are being explored in ...

为探究泌尿生殖系统损伤的遗传病因，研究人员对患者进行研究，发现 WT1 基因新变异与 MGD 及肾病有关，意义重大。 在生命的奇妙旅程中，人体的发育就像一部精密的交响乐，每个基因都是其中的音符，奏响着成长的旋律。然而，当某些关键基因出现 “变奏 ...

A thyroglobulin antibody (TgAb) test looks for certain antibodies that attack the thyroid. The presence of TbAb in high levels may indicate that someone has an autoimmune condition. To conduct a ...

Monoclonal antibodies have specificity for a particular antigen (target of antibodies), but polyclonal ones are not specific to any antigen. Recombinant ones are monoclonal, and here are the key ...

Bispecific antibodies seem to be all the rage at the minute. Their ability to deliver targeted therapeutics to patients with a two-in-one approach by simultaneously binding to two different antigens ...

The cyclic citrullinated peptide (CCP) test measures CCP antibodies in the blood. These proteins are part of an immune system attack on healthy tissues and cells, such as the joints. A healthcare ...

Offering a two-in-one approach to delivering targeted therapeutics to patients and providing a versatile solution to the challenges associated with the co-administration of drugs, bispecific ...

Antibodies are crucial in therapeutics and immune defense, but their hypervariable regions pose challenges for computational modeling. We introduce Antibody Mutagenesis-Augmented Processing (AbMAP), a ...

The efficacy and safety of intravenous Lu AG09222, a humanized monoclonal antibody directed against the PACAP ligand, for migraine prevention are unclear. In a phase 2, double-blind, randomized ...

Doctors may order a cyclic citrullinated peptide (CCP) antibody test and other exams to confirm or rule out a rheumatoid arthritis (RA) diagnosis. A positive CCP antibody test doesn’t ...

And there is plenty of evidence that one of these fields is monoclonal antibody (mAb) discovery. It has long benefited from applications of wet chemistry and analytics. And now it is starting to ...