No writing assistance was utilized in the production of this manuscript. Monoclonal antibodies are novel therapeutic agents used with great success in the treatment of rheumatoid arthritis (RA).

Antibodies are secreted immunoglobulin molecules produced mainly by plasma cells. The antigen-binding site of the antibody has a unique structure that allows it to bind antigen in a highly ...

TIGIT, in particular, has proved to be a tricky target for drug developers, and BeiGene's decision comes just a few months after MSD abandoned the development of its anti-TIGIT antibody ...

The potential of monoclonal antibodies (mAbs) as therapies is indisputable. The current mAbs market is expected to be around ~USD 150 billion. In 2021, five out of the top 10 selling drugs were ...

The latter occurs most notably in the neonate as a result of a mother with antibodies due to AITD. TPO antibodies (TPOAb) appear involved in the tissue destructive processes associated with the ...

The blood-brain barrier (BBB) restricts systemically delivered therapeutic antibodies into the brain. Here the authors engineer antibody Fc region to promote the binding to BBB expressed neonatal ...

A new study shows that a series of vaccines can coax the immune system to produce powerful antibodies capable of blocking a wide range of HIV strains—including those that are typically the ...

Pacibekitug, an antibody targeting interleukin-6, hit the primary endpoint in the phase 2 Tranquility trial by sharply reducing levels of C-reactive protein (CRP), a biomarker for cardiovascular ...

Researchers from Ludwig Cancer Research have developed an antibody, PLT012, that targets the lipid transporter CD36 to reverse immune suppression in fat-rich tumor environments, restoring anti-tumor ...

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GAS produces a toxic enzyme known as streptolysin O. Your immune system produces antibodies to fight this toxic enzyme. One of these antibodies is called antistreptolysin O (ASO). An ...